Plant Transcription Factor Database
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G08790.1
Common Nameanac081, ATAF2, NAC081, T2K12.140
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family NAC
Protein Properties Length: 283aa    MW: 32225.2 Da    PI: 5.4696
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G08790.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
          NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkge 98 
                  lp+GfrFhPtdeelv++yL++k++++++++  vi+e+d+yk++Pw+Lp++   +ekewyfFs+rd+ky++g+r+nra+ +gyWkatg dk++ +   +
                  799*************************99.89***************66566899************************************98..77 PP

          NAM  99 lvglkktLvfykgrapkgektdWvmheyrl 128
                  + g+kk Lvfy g+apkg kt+W+mheyrl
                  8***************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019412.35E-604159IPR003441NAC domain
PROSITE profilePS5100559.0097159IPR003441NAC domain
PfamPF023657.1E-278131IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007275Biological Processmulticellular organism development
GO:0008361Biological Processregulation of cell size
GO:0009416Biological Processresponse to light stimulus
GO:0009611Biological Processresponse to wounding
GO:0009620Biological Processresponse to fungus
GO:0009744Biological Processresponse to sucrose
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0043424Molecular Functionprotein histidine kinase binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
PO:0003018anatomyroot cap of lateral root
PO:0006340anatomyadult vascular leaf
PO:0020121anatomylateral root
Sequence ? help Back to Top
Protein Sequence    Length: 283 aa     Download sequence    Send to blast
3D Structure ? help Back to Top
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ulx_A5e-84216510174Stress-induced transcription factor NAC1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.278260.0flower| inflorescence| leaf| root| seed
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT5G08790
Functional Description ? help Back to Top
Source Description
TAIRinduced by wounding, belongs to a large family of putative transcriptional activators with NAC domain.
Function -- GeneRIF ? help Back to Top
  1. ATAF2 overexpressing plants showed a higher susceptibility to the soil-borne fungal pathogen F.oxysporum, and repression of a number of pathogenesis-related proteins.
    [PMID: 16115070]
  2. The identification of a cis-regulatory binding sequence for ATAF2, is reported.
    [PMID: 22937923]
  3. ATAF2 regulates NIT2 gene expression via NIT2 promoter binding.
    [PMID: 22965747]
  4. ATAF2 acts as a central regulator of plant defense, hormone metabolism and light-mediated seedling development
    [PMID: 26493403]
Cis-element ? help Back to Top
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDjasmonic acid, salicylic acid
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9C598
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G08790
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2288030.0AK228803.1 Arabidopsis thaliana mRNA for ATAF2 protein, complete cds, clone: RAFL16-12-H06.
GenBankAY0808620.0AY080862.1 Arabidopsis thaliana unknown protein (At5g08790) mRNA, complete cds.
GenBankAY1337620.0AY133762.1 Arabidopsis thaliana clone U18877 unknown protein (At5g08980) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_680161.10.0protein ATAF2
SwissprotQ9C5980.0NAC81_ARATH; Protein ATAF2
TrEMBLD7M2080.0D7M208_ARALL; Putative uncharacterized protein
STRINGAT5G08790.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP1715800
Publications ? help Back to Top
  1. Collinge M,Boller T
    Differential induction of two potato genes, Stprx2 and StNAC, in response to infection by Phytophthora infestans and to wounding.
    Plant Mol. Biol., 2001. 46(5): p. 521-9
  2. Seki M, et al.
    Functional annotation of a full-length Arabidopsis cDNA collection.
    Science, 2002. 296(5565): p. 141-5
  3. Mart
    Genomic analysis of the unfolded protein response in Arabidopsis shows its connection to important cellular processes.
    Plant Cell, 2003. 15(2): p. 561-76
  4. Greve K,La Cour T,Jensen MK,Poulsen FM,Skriver K
    Interactions between plant RING-H2 and plant-specific NAC (NAM/ATAF1/2/CUC2) proteins: RING-H2 molecular specificity and cellular localization.
    Biochem. J., 2003. 371(Pt 1): p. 97-108
  5. Hammond JP, et al.
    Changes in gene expression in Arabidopsis shoots during phosphate starvation and the potential for developing smart plants.
    Plant Physiol., 2003. 132(2): p. 578-96
  6. Ekman DR,Lorenz WW,Przybyla AE,Wolfe NL,Dean JF
    SAGE analysis of transcriptome responses in Arabidopsis roots exposed to 2,4,6-trinitrotoluene.
    Plant Physiol., 2003. 133(3): p. 1397-406
  7. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
  8. Hegedus D, et al.
    Molecular characterization of Brassica napus NAC domain transcriptional activators induced in response to biotic and abiotic stress.
    Plant Mol. Biol., 2003. 53(3): p. 383-97
  9. Ooka H, et al.
    Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis thaliana.
    DNA Res., 2003. 10(6): p. 239-47
  10. Ernst HA,Olsen AN,Larsen S,Lo Leggio L
    Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors.
    EMBO Rep., 2004. 5(3): p. 297-303
  11. Delessert C, et al.
    The transcription factor ATAF2 represses the expression of pathogenesis-related genes in Arabidopsis.
    Plant J., 2005. 43(5): p. 745-57
  12. Nakano T, et al.
    Identification of genes of the plant-specific transcription-factor families cooperatively regulated by ethylene and jasmonate in Arabidopsis thaliana.
    J. Plant Res., 2006. 119(4): p. 407-13
  13. Zhong R,Demura T,Ye ZH
    SND1, a NAC domain transcription factor, is a key regulator of secondary wall synthesis in fibers of Arabidopsis.
    Plant Cell, 2006. 18(11): p. 3158-70
  14. Soitamo AJ,Piippo M,Allahverdiyeva Y,Battchikova N,Aro EM
    Light has a specific role in modulating Arabidopsis gene expression at low temperature.
    BMC Plant Biol., 2008. 8: p. 13
  15. Dortay H, et al.
    Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana.
    J. Proteome Res., 2008. 7(9): p. 3649-60
  16. Abercrombie JM, et al.
    Transcriptional responses of Arabidopsis thaliana plants to As (V) stress.
    BMC Plant Biol., 2008. 8: p. 87
  17. Kunieda T, et al.
    NAC family proteins NARS1/NAC2 and NARS2/NAM in the outer integument regulate embryogenesis in Arabidopsis.
    Plant Cell, 2008. 20(10): p. 2631-42
  18. Wang X,Goregaoker SP,Culver JN
    Interaction of the Tobacco mosaic virus replicase protein with a NAC domain transcription factor is associated with the suppression of systemic host defenses.
    J. Virol., 2009. 83(19): p. 9720-30
  19. Miller MJ,Barrett-Wilt GA,Hua Z,Vierstra RD
    Proteomic analyses identify a diverse array of nuclear processes affected by small ubiquitin-like modifier conjugation in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2010. 107(38): p. 16512-7
  20. Wang X,Culver JN
    DNA binding specificity of ATAF2, a NAC domain transcription factor targeted for degradation by Tobacco mosaic virus.
    BMC Plant Biol., 2012. 12: p. 157
  21. Huh SU,Lee SB,Kim HH,Paek KH
    ATAF2, a NAC transcription factor, binds to the promoter and regulates NIT2 gene expression involved in auxin biosynthesis.
    Mol. Cells, 2012. 34(3): p. 305-13
  22. Zhao J,Favero DS,Peng H,Neff MM
    Arabidopsis thaliana AHL family modulates hypocotyl growth redundantly by interacting with each other via the PPC/DUF296 domain.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(48): p. E4688-97
  23. Peng H,Zhao J,Neff MM
    ATAF2 integrates Arabidopsis brassinosteroid inactivation and seedling photomorphogenesis.
    Development, 2015. 142(23): p. 4129-38